| Also known as: |
CD51/CD61 |
| Other names: |
Integrin beta-3, Platelet membrane glycoprotein IIIa, antigen CD61), beta 3 (platelet glycoprotein IIIa, integrin, integrin beta-3, platelet membrane glycoprotein IIIa, integrin beta-3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD51/CD61 |
| Other gene names: |
BDPLT2, CD61, GP3A, GP3A, GPIIIa, GPIIIa, GT, ITGB3, ITGB3 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
23C6 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
23C6 reacts with osteoclasts, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This complex binds vitronectin at the RGD sequence and can also bind fibrinogen, This particular antibody might cross react with speacies outside of the listed ones, fibronectin, melanoma cell lines and weakly with platelets, osteopontin and collagen, placenta, thrombospondin, von Willebrand factor, CD51/CD61 This item recognises the intact complex formed between the CD51 and CD61 molecules (alpha V and beta 3 integrins) |
| Form/Appearance: |
Azide Free (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
Immunohistology - Frozen (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD51/CD61: |
| Short name: |
MOUSE Anti-HUMAN CD51/CD61:Azide Free Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD51/CD61:Azide Free (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
6150 |
| Gene: |
ITGAV |
More about : ITGAV |
| Long gene name: |
integrin subunit alpha V |
| Synonyms gene: |
VNRA MSK8 VTNR |
| Synonyms gene name: |
alpha V , alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) integrin, antigen identified by monoclonal antibody L230 vitronectin receptor integrin |
| Synonyms: |
CD51 |
| Locus: |
2q32, 1 |
| Discovery year: |
1988-07-19 |
| Entrez gene record: |
3685 |
| Pubmed identfication: |
2454952 |
| RefSeq identity: |
NM_002210 |
| Classification: |
Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000132635 |