| Also known as: |
CD51 |
| Other names: |
Integrin alpha-V, Vitronectin receptor subunit alpha, alphav-integrin, integrin alpha V, integrin alpha-V, vitronectin receptor alpha polypeptide (VNRA), vitronectin receptor subunit alpha, integrin alpha-V |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD51 |
| Other gene names: |
1110004F14Rik, 2610028E01Rik, CD51, D430040G12Rik, Itgav, N/A, Itgav |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
RMV-7 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Alpha-V integrins may play a role in embryo implantation, CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61, CD51/CD61 is primarily expressed on myeloid cells and activated T-cells, Heterodimers of CD51/CD61 function as a receptor for vitronectin, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, This particular antibody might cross react with speacies outside of the listed ones, a 140 kD alpha subunit of the vitronectin receptor, and CD31 in some cell types, and a wide array of RGD-containing proteins including fibronectin, angiogenesis and wound healing, as well as blocking LAK cell cytotoxicity , fibrinogen, fibronectin, laminin, thrombospondin and osteopontin, von Willebrand factor, which is otherwise known as the integrin alpha v chain, CD51 This item recognises murine CD51 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Frozen (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD51 |
| Short name: |
RAT ANTI MOUSE CD51 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD51 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6150 |
| Gene: |
ITGAV |
More about : ITGAV |
| Long gene name: |
integrin subunit alpha V |
| Synonyms gene: |
VNRA MSK8 VTNR |
| Synonyms gene name: |
alpha V , alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) integrin, antigen identified by monoclonal antibody L230 vitronectin receptor integrin |
| Synonyms: |
CD51 |
| Locus: |
2q32, 1 |
| Discovery year: |
1988-07-19 |
| Entrez gene record: |
3685 |
| Pubmed identfication: |
2454952 |
| RefSeq identity: |
NM_002210 |
| Classification: |
Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000132635 |