| known also as: |
Anti-RABBIT ANTI SHP2 (C-TERMINAL) |
| known also as: |
RABBIT ANTI SHP2 (C-TERMINAL) |
| known also as: |
Lapin ANTI SHP2 (C-TERMINAL) |
| known also as: |
SHP2 |
| Other names: |
PTP-1D, PTP-2C, PTP-2C, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, SH-PTP2, SH-PTP3, SHP-2, Shp2, Tyrosine-protein phosphatase non-receptor type 11, non-receptor type 11, protein tyrosine phosphatase, protein-tyrosine phosphatase 1D, protein-tyrosine phosphatase 2C, tyrosine-protein phosphatase non-receptor type 11, tyrosine-protein phosphatase non-receptor type 11 isoform 1 |
| Gene name: |
SHP2 |
| Other gene names: |
BPTP3, CFC, NS1, PTP-1D, PTP-1D, PTP-2C, PTP2C, PTP2C, PTPN11, SH-PTP2, SH-PTP3, SHP-2, SHP2, SHPTP2, Shp2, PTPN11 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
As a result, Noonan and Noonan-like syndrome as well as acute myeloid leukaemia, SHP2 acts downstream of growth factor receptors and cytoplasmic protein tyrosine kinases which transduce signals from cell surface to the nucleus, SHP2 is ubiquitously expressed, The recruitment and activation of SHP2 is mediated through the binding of CD172a to its ligand CD47, These include transcription, a 68 kDa member of the protein tyrosine phosphatase family, and skeletal muscle, brain, cell growth, cell migration, differentiation, dysregulation of the SHP2 gene has been linked to LEOPARD, embryonic development, haematopoiesis and oncogenic transformation, mitotic cycle, with highest levels found in heart, SHP2 This item recognises src homology 2 domain containing tyrosine phosphatase (SHP2), _x000D_SHP2 regulates a variety of cellular processes |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
SHP2 |
| Short name: |
Anti-SHP2 (C-TERMINAL) |
| Alternative name: |
antibody to-SHP2 (C-TERMINAL) |
| Identity: |
9644 |
| Gene: |
PTPN11 |
More about : PTPN11 |
| Long gene name: |
non-receptor type 11 , protein tyrosine phosphatase |
| Synonyms gene: |
NS1 |
| Synonyms gene name: |
Noonan syndrome 1 |
| Synonyms: |
BPTP3 SH-PTP2 SHP-2 PTP2C SHP2 |
| Locus: |
12q24, 13 |
| Discovery year: |
1993-03-03 |
| GenBank acession: |
D13540 |
| Entrez gene record: |
5781 |
| Pubmed identfication: |
7894486 1280823 |
| Classification: |
Protein tyrosine phosphatases, non-receptor type SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000134334 |
| Locus Specific Databases: |
LRG_614 |