| Long name: |
ALEXA FLUOR 647 Conjugated, KCTD11 Polyclonal Antibody |
| Also known as: |
Anti-KCTD11 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
KCTD11 |
| Specificity: |
This is a highly specific antibody against KCTD11 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KCTD11 |
| Gene ID Number: |
147040 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcrition factor GLI1, Induces apoptosis, Its inactivation might lead to a deregulation of the tumor promoting Hedgehog pathway in medulloblastoma, Plays a role as a marker and a regulator of neuronal differentiation, Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB), Up-regulated by a variety of neurogenic signals, epidermal growth factor/EGF and NGFB/nerve growth factor, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B, such as retinoic acid, thus maintaining cerebellar granule cells in undifferentiated state, The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
REN KCASH1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the KCTD11 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
KCTD11 |
| Short name: |
KCTD11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, KCTD11 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21302 |
| Gene: |
KCTD11 |
More about : KCTD11 |
| Long gene name: |
potassium channel tetramerization domain containing 11 |
| Synonyms gene: |
C17orf36 |
| Synonyms gene name: |
chromosome 17 open reading frame 36 potassium channel tetramerisation domain containing 11 |
| Locus: |
17p13, 1 |
| Discovery year: |
2003-06-10 |
| GenBank acession: |
AK056227 |
| Entrez gene record: |
147040 |
| Pubmed identfication: |
12186855 21472142 |
| RefSeq identity: |
NM_001002914 |
| Havana BLAST/BLAT: |
OTTHUMG00000132061 |