| Long name: |
ALEXA FLUOR 555 Conjugated, KCTD11 Polyclonal Antibody |
| Also known as: |
Anti-KCTD11 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
KCTD11 |
| Specificity: |
This is a highly specific antibody against KCTD11 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KCTD11 |
| Gene ID Number: |
147040 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcrition factor GLI1, Induces apoptosis, Its inactivation might lead to a deregulation of the tumor promoting Hedgehog pathway in medulloblastoma, Plays a role as a marker and a regulator of neuronal differentiation, Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB), Up-regulated by a variety of neurogenic signals, epidermal growth factor/EGF and NGFB/nerve growth factor, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B, such as retinoic acid, thus maintaining cerebellar granule cells in undifferentiated state, The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
REN KCASH1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
KCTD11 |
| Short name: |
KCTD11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, KCTD11 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21302 |
| Gene: |
KCTD11 |
More about : KCTD11 |
| Long gene name: |
potassium channel tetramerization domain containing 11 |
| Synonyms gene: |
C17orf36 |
| Synonyms gene name: |
chromosome 17 open reading frame 36 potassium channel tetramerisation domain containing 11 |
| Locus: |
17p13, 1 |
| Discovery year: |
2003-06-10 |
| GenBank acession: |
AK056227 |
| Entrez gene record: |
147040 |
| Pubmed identfication: |
12186855 21472142 |
| RefSeq identity: |
NM_001002914 |
| Havana BLAST/BLAT: |
OTTHUMG00000132061 |