| Long name: |
Cy5, 5 Conjugated, RPE65 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RPE65 |
| Specificity: |
This is a highly specific antibody against RPE65 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human RPE65 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2, RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated, Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the Î, The soluble form of the protein binds vitamin A, This protein is important in 11-cis retinal production as well as in visual pigment regeneration, ², -carotene dioxygenase family, The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
LCA2 rd12 BCO3 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
RPE65 Conjugated |
| Short name: |
Conjugated, RPE65 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, RPE65 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10294 |
| Gene: |
RPE65 |
More about : RPE65 |
| Long gene name: |
RPE65, retinoid isomerohydrolase |
| Synonyms gene: |
RP20 |
| Synonyms gene name: |
retinal pigment epithelium-specific protein 65kDa |
| Synonyms name: |
BCO family, member 3 retinol isomerase all-trans-retinyl-palmitate hydrolase |
| Locus: |
1p31, 3 |
| Discovery year: |
1993-10-04 |
| GenBank acession: |
U18991 |
| Entrez gene record: |
6121 |
| Pubmed identfication: |
8340400 16116091 |
| RefSeq identity: |
NM_000329 |
| Havana BLAST/BLAT: |
OTTHUMG00000009208 |
| Locus Specific Databases: |
Mutations of the RPE65 Gene |