| Long name: |
RPE65 Primary Polyclonal Antibody |
| Also known as: |
RPE65 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RPE65 |
| Specificity: |
This is a highly specific antibody against RPE65 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RPE65 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2, RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated, Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the Î, The soluble form of the protein binds vitamin A, This protein is important in 11-cis retinal production as well as in visual pigment regeneration, ², -carotene dioxygenase family, The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
LCA 2, LCA2, Leber congenital amaurosis, RP 20, RP20, RPE 65, RPE65, RPE65_HUMAN, Retinal pigment epithelium specic 61 kDa protein, Retinal pigment epithelium specic 65 kDa protein, Retinal pigment epithelium specic protein, Retinal pigment epithelium specic protein 65kDa, Retinal pigment epithelium-specic 65 kDa protein, Retinitis pigmentosa 20, Retinoid isomerohydrolase, mRPE 65, mRPE65, p63, rd 12, rd12, sRPE 65, sRPE65, All-trans-retinyl-palmitate hydrolase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RPE65 |
| Short name: |
RPE65 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RPE65 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10294 |
| Gene: |
RPE65 |
More about : RPE65 |
| Long gene name: |
RPE65, retinoid isomerohydrolase |
| Synonyms gene: |
RP20 |
| Synonyms gene name: |
retinal pigment epithelium-specific protein 65kDa |
| Synonyms: |
LCA2 rd12 BCO3 |
| Synonyms name: |
BCO family, member 3 retinol isomerase all-trans-retinyl-palmitate hydrolase |
| Locus: |
1p31, 3 |
| Discovery year: |
1993-10-04 |
| GenBank acession: |
U18991 |
| Entrez gene record: |
6121 |
| Pubmed identfication: |
8340400 16116091 |
| RefSeq identity: |
NM_000329 |
| Havana BLAST/BLAT: |
OTTHUMG00000009208 |
| Locus Specific Databases: |
Mutations of the RPE65 Gene |