| Long name: |
FITC Conjugated, HMBS Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HMBS |
| Specificity: |
This is a highly specific antibody against HMBS |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human HMBS/PBGD |
| Gene ID number: |
3145 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
AIP is characterized by acute attacks of neurological dysfunctions with hypertension, Deficiency of PBGD causes errors in pyrrole metabolism, PBGD belongs to the HMBS (hydroxymethylbilane synthase) family, abdominal pain and excessive amounts of aminolevulinic acid and porphobilinogen in the urine, also designated hydroxymethylbilane synthase, is a cytoplasmic enzyme found in the heme synthesis pathway, peripheral neurologic disturbances, tachycardia, which in turn leads to an inherited autosomal disorder called acute intermittent porphyria (AIP), PBGD |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HMBS Conjugated |
| Short name: |
FITC Conjugated, HMBS Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, HMBS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4982 |
| Gene: |
HMBS |
More about : HMBS |
| Long gene name: |
hydroxymethylbilane synthase |
| Synonyms gene: |
PBGD UPS PORC |
| Synonyms gene name: |
Chester type , acute, uroporphyrinogen I synthase porphobilinogen deaminase porphyria |
| Locus: |
11q23, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X04808 |
| Entrez gene record: |
3145 |
| Pubmed identfication: |
8432552 17298217 |
| RefSeq identity: |
NM_000190 |
| Havana BLAST/BLAT: |
OTTHUMG00000168295 |
| Locus Specific Databases: |
LRG_1076 |