| Long name: |
ALEXA FLUOR 488 Conjugated, HMBS Polyclonal Antibody |
| Also known as: |
Anti-HMBS PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HMBS |
| Specificity: |
This is a highly specific antibody against HMBS |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HMBS/PBGD |
| Gene ID Number: |
3145 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
AIP is characterized by acute attacks of neurological dysfunctions with hypertension, Deficiency of PBGD causes errors in pyrrole metabolism, PBGD belongs to the HMBS (hydroxymethylbilane synthase) family, abdominal pain and excessive amounts of aminolevulinic acid and porphobilinogen in the urine, also designated hydroxymethylbilane synthase, is a cytoplasmic enzyme found in the heme synthesis pathway, peripheral neurologic disturbances, tachycardia, which in turn leads to an inherited autosomal disorder called acute intermittent porphyria (AIP), PBGD |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the HMBS Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
HMBS |
| Short name: |
HMBS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, HMBS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4982 |
| Gene: |
HMBS |
More about : HMBS |
| Long gene name: |
hydroxymethylbilane synthase |
| Synonyms gene: |
PBGD UPS PORC |
| Synonyms gene name: |
Chester type , acute, uroporphyrinogen I synthase porphobilinogen deaminase porphyria |
| Locus: |
11q23, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X04808 |
| Entrez gene record: |
3145 |
| Pubmed identfication: |
8432552 17298217 |
| RefSeq identity: |
NM_000190 |
| Havana BLAST/BLAT: |
OTTHUMG00000168295 |
| Locus Specific Databases: |
LRG_1076 |