| Long name: |
HMBS Primary Polyclonal Antibody |
| Also known as: |
HMBS PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
HMBS |
| Specificity: |
This is a highly specific antibody against HMBS |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HMBS/PBGD |
| Gene ID number: |
3145 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
AIP is characterized by acute attacks of neurological dysfunctions with hypertension, Deficiency of PBGD causes errors in pyrrole metabolism, PBGD belongs to the HMBS (hydroxymethylbilane synthase) family, abdominal pain and excessive amounts of aminolevulinic acid and porphobilinogen in the urine, also designated hydroxymethylbilane synthase, is a cytoplasmic enzyme found in the heme synthesis pathway, peripheral neurologic disturbances, tachycardia, which in turn leads to an inherited autosomal disorder called acute intermittent porphyria (AIP), PBGD |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
HMBS, Hydroxymethylbilane synthase, PBG D, PBG-D, PBGD, Porphobilinogen deaminase, Pre uroporphyrinogen synthase, Pre-uroporphyrinogen synthase, UPS, Uroporphyrinogen I synthase, Uroporphyrinogen I synthetase, HEM3_HUMAN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HMBS |
| Short name: |
HMBS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HMBS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4982 |
| Gene: |
HMBS |
More about : HMBS |
| Long gene name: |
hydroxymethylbilane synthase |
| Synonyms gene: |
PBGD UPS PORC |
| Synonyms gene name: |
Chester type , acute, uroporphyrinogen I synthase porphobilinogen deaminase porphyria |
| Locus: |
11q23, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X04808 |
| Entrez gene record: |
3145 |
| Pubmed identfication: |
8432552 17298217 |
| RefSeq identity: |
NM_000190 |
| Havana BLAST/BLAT: |
OTTHUMG00000168295 |
| Locus Specific Databases: |
LRG_1076 |