| Long name: |
Biotin Conjugated, OSTM1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OSTM1 |
| Specificity: |
This is a highly specific antibody against OSTM1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
32-88/334 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human OSTM1 |
| Gene ID number: |
28962 |
| Swiss Prot: |
Q86WC4 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ARO is suggested to be caused by mutations in the OSTM1 gene, Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, also known as gl (gray-lethal) or HSPC019, and a benign autosomal dominant form occurring in adolescence or adulthood, due to defective resorption of immature bone, infancy, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen, or childhood, which is responsible for a coat color defect in mice, OSTM1 (osteopetrosis associated transmembrane protein 1) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
HSPC019 GL |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
OSTM1 Conjugated |
| Short name: |
Conjugated, OSTM1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, OSTM1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21652 |
| Gene: |
OSTM1 |
More about : OSTM1 |
| Long gene name: |
osteopetrosis associated transmembrane protein 1 |
| Synonyms name: |
CLCN7 accessory beta subunit |
| Locus: |
6q21 |
| Discovery year: |
2003-10-06 |
| GenBank acession: |
AF533891 |
| Entrez gene record: |
28962 |
| Pubmed identfication: |
12627228 21527911 |
| RefSeq identity: |
NM_014028 |
| Havana BLAST/BLAT: |
OTTHUMG00000015317 |