| Long name: |
ALEXA FLUOR 594 Conjugated, OSTM1 Polyclonal Antibody |
| Also known as: |
Anti-OSTM1 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OSTM1 |
| Specificity: |
This is a highly specific antibody against OSTM1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
32-88/334 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OSTM1 |
| Gene ID Number: |
28962 |
| Swiss Prot: |
Q86WC4 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
ARO is suggested to be caused by mutations in the OSTM1 gene, Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, also known as gl (gray-lethal) or HSPC019, and a benign autosomal dominant form occurring in adolescence or adulthood, due to defective resorption of immature bone, infancy, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen, or childhood, which is responsible for a coat color defect in mice, OSTM1 (osteopetrosis associated transmembrane protein 1) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HSPC019 GL |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
OSTM1 |
| Short name: |
OSTM1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, OSTM1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21652 |
| Gene: |
OSTM1 |
More about : OSTM1 |
| Long gene name: |
osteopetrosis associated transmembrane protein 1 |
| Synonyms name: |
CLCN7 accessory beta subunit |
| Locus: |
6q21 |
| Discovery year: |
2003-10-06 |
| GenBank acession: |
AF533891 |
| Entrez gene record: |
28962 |
| Pubmed identfication: |
12627228 21527911 |
| RefSeq identity: |
NM_014028 |
| Havana BLAST/BLAT: |
OTTHUMG00000015317 |