| Long name: |
OSTM1 Primary Polyclonal Antibody |
| Also known as: |
OSTM1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
OSTM1 |
| Specificity: |
This is a highly specific antibody against OSTM1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
32-88/334 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OSTM1 |
| Gene ID number: |
28962 |
| Swiss Prot: |
Q86WC4 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ARO is suggested to be caused by mutations in the OSTM1 gene, Bone autosomal recessive osteopetrosis (ARO) is the most severe form of hereditary bone disease whose cellular basis is in the osteoclast and is characterized by abnormally dense bone, Defects in the OSTM1 gene are also the cause of the spontaneous gl mutant, The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, also known as gl (gray-lethal) or HSPC019, and a benign autosomal dominant form occurring in adolescence or adulthood, due to defective resorption of immature bone, infancy, is a 338 amino acid single-pass type I membrane protein that is expressed primarily in osteoclasts and melanocytes as well as brain, kidney and spleen, or childhood, which is responsible for a coat color defect in mice, OSTM1 (osteopetrosis associated transmembrane protein 1) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Chloride channel 7 beta subunit, GIPN, HSPC019, OPTB5, OSTM1, Osteopetrosis-associated transmembrane protein 1, UNQ6098/PRO21201, GL |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
OSTM1 |
| Short name: |
OSTM1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
OSTM1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21652 |
| Gene: |
OSTM1 |
More about : OSTM1 |
| Long gene name: |
osteopetrosis associated transmembrane protein 1 |
| Synonyms: |
HSPC019 GL |
| Synonyms name: |
CLCN7 accessory beta subunit |
| Locus: |
6q21 |
| Discovery year: |
2003-10-06 |
| GenBank acession: |
AF533891 |
| Entrez gene record: |
28962 |
| Pubmed identfication: |
12627228 21527911 |
| RefSeq identity: |
NM_014028 |
| Havana BLAST/BLAT: |
OTTHUMG00000015317 |