LRDD Antibody, Cy5.5 Conjugated

Catalog number:	bs-7615R-Cy5.5 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	LRDD Antibody, Cy5.5 Conjugated
Quantity:	0.1ml
Related search:	pidd antibody antibodies gene domain year

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Long name:	Cy5, 5 Conjugated, LRDD Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Cy5, 5, 5, Cy5
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	LRDD
Specificity:	This is a highly specific antibody against LRDD
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic peptide derived from human LRDD/PIDD
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Increased PIDD expression results in spontaneous activation of caspase-2 and sensitization to apoptosis by genotoxic stimuli, Independently, PIDD also promotes apoptosis downstream of p53 as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis, PIDD forms a complex with caspase-2 and the adaptor protein RAIDD, PIDD has also been shown to interact with NEMO/IKBKG and RIP1 and enhance sumoylation and ubiquitination of NEMO/IKBKG, PIDD was also described as a DD-containing protein with unknown function, The N-terminal region of PIDD contains seven leucine-rich repeats (LRRs), a protein interaction motif found in various proteins with diverse functions, an important component for activation of the transcription factor NF-kappa-B, followed by two ZU-5 domains and a C-terminal DD, via interaction with caspase-2 and CRADD/RAIDD, The death domain (DD) containing protein PIDD is a p53 target gene in an erythroleukemia cell line that undergoes G1 phase arrest and subsequent apoptosis after p53 expression
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	675nm/694nm
Synonyms:	MGC16925 DKFZp434D229
Properties:	Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated:	These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene target:	LRDD Conjugated
Short name:	Conjugated, LRDD Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	5, Cy5
Alternative name:	cyanine 5, 5 coupled, LRDD (Antibody to)
Alternative technique:	antibodies
Identity:	16491
Gene:	PIDD1 | More about : PIDD1
Long gene name:	p53-induced death domain protein 1
Synonyms gene:	LRDD PIDD
Synonyms gene name:	leucine-rich repeats and death domain containing p53-induced death domain protein
Locus:	11p15, 5
Discovery year:	2001-09-04
GenBank acession:	AF229178
Entrez gene record:	55367
Pubmed identfication:	10825539
RefSeq identity:	NM_145886
Havana BLAST/BLAT:	OTTHUMG00000133306

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