| Long name: |
ALEXA FLUOR 555 Conjugated, Fibrinogen alpha chain Antibody |
| Also known as: |
Anti-Fibrinogen alpha chain PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Fibrinogen alpha chain |
| Specificity: |
This is a highly specific antibody against Fibrinogen alpha chain |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
70-105/866 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibrinogen alpha chain |
| Gene ID Number: |
2243 |
| Swiss Prot: |
P02671 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway, Fibrin deposition is also associated with infection, Fibrin has a major function in hemostasis as one of the primary components of blood clots, However, In addition, Maternal fibrinogen is essential for successful pregnancy, May also facilitate the immune response via both innate and T-cell mediated pathways, Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization, polymerize to form an insoluble fibrin matrix, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), where it protects against IFNG-mediated hemorrhage, Cleaved by the protease thrombin to yield monomers which |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
Fibrinogen alpha chain |
| Short name: |
Fibrinogen alpha chain Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, Fibrinogen a epitope (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3661 |
| Gene: |
FGA |
More about : FGA |
| Long gene name: |
fibrinogen alpha chain |
| Synonyms gene name: |
A alpha polypeptide , fibrinogen |
| Locus: |
4q31, 3 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
2243 |
| RefSeq identity: |
NM_000508 |
| Classification: |
Endogenous ligands Fibrinogen C domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000150330 |
| Locus Specific Databases: |
A Database For Human Fibrinogen Variants LRG_557 |