| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Fibrinogen gamma chain |
| Specificity: |
This antibody reacts specifically with Fibrinogen gamma chain |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Helical, Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Fibrinogen gamma chain |
| Gene ID: |
2266 |
| Swiss Prot: |
P02679 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway, Fibrin deposition is also associated with infection, Has a major function in hemostasis as one of the primary components of blood clots, However, In addition, Maternal fibrinogen is essential for successful pregnancy, May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways, Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization, polymerizes to form an insoluble fibrin matrix, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo, where it protects against IFNG-mediated hemorrhage, Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FGG, PRO2061, Fibrinogen gamma chain |
| Also known as: |
Fibrinogen gamma chain Antibody |
| Other name: |
Anti-Fibrinogen gamma chain |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Fibrinogen gamma chain |
| Short name: |
Fluor 594, Anti-Fibrinogen gamma chain |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Fibrinogen g epitope |