Long name: |
ALEXA FLUOR 555 Conjugated, Bovine Fibrinogen Polyclonal Antibody |
Also known as: |
Anti-Bovine Fibrinogen PAb ALEXA FLUOR 555 |
Category: |
Conjugated Primary Antibodies |
Conjugated with: |
555, ALEXA FLUOR® |
Host Organism: |
Rabbit (Oryctolagus cuniculus) |
Target Antigen: |
Bovine Fibrinogen |
Specificity: |
This is a highly specific antibody against Bovine Fibrinogen |
Modification: |
Unmodified |
Modification Site: |
None |
Clonality: |
Polyclonal |
Clone: |
Polyclonal antibody |
Concentration: |
1ug per 1ul |
Source: |
Fibrinogen from bovine plasma |
Gene ID Number: |
522039 |
Tested applications: |
IF(IHC-P) |
Recommended dilutions: |
IF(IHC-P)(1:50-200) |
Crossreactivity: |
Bovine |
Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
Background of the antigen: |
All chains are connected with each other by a number of disulfide bonds, All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases, An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A, Fibrinogen activation is also involved in pathogenesis of inflammation, Fibrinogen clotting underlies pathogenesis of MI, Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, In this way fibrinogen is converted into fibrin, It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases, The normal fibrinogen concentration in plasma is about 3 mg/ml, and Rapold H, beta and gamma, et al, et al), respectively, since fibrin is the main substrate for thrombus formation, thromboembolism and thromboses of arteries and veins, tumor growth and many other diseases, which by means of polymerization forms a fibrin clot, Fibrinogen is the main protein of blood coagulation system, J |
Purification: |
Purified by Protein A |
Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
Excitation emission: |
553nm/568nm |
Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
Gene target: |
Fibrinogen |
Short name: |
Fibrinogen Antibody |
Technique: |
antibodies against human proteins, antibodies for, Antibody |
Label: |
ALEXA FLUOR 555 |
Species: |
Bos Taurus genes are available form the Bovine Genome database, Bovine |
Alternative name: |
ALEXA FLUOR 555, Bovine Fibrinogen (Antibody to) |
Alternative technique: |
antibodies |
Identity: |
43653 |
Gene: |
FSBP |
More about : FSBP |
Long gene name: |
fibrinogen silencer binding protein |
Locus: |
8q22, 1 |
Discovery year: |
2012-01-10 |
Entrez gene record: |
100861412 |
Pubmed identfication: |
20531236 |
RefSeq identity: |
NM_001256141 |
Havana BLAST/BLAT: |
OTTHUMG00000178341 |