| Long name: |
ALEXA FLUOR 647 Conjugated, Scavenger Receptor BII Antibody |
| Also known as: |
Anti-Scavenger Receptor BII PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Scavenger Receptor BII |
| Specificity: |
This is a highly specific antibody against Scavenger Receptor BII |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
222-242/478 |
| Subcellular location: |
Helical |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Scavenger Receptor BII |
| Gene ID Number: |
950 |
| Swiss Prot: |
Q14108 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Although the role of these scavenger receptors is not completely clear, Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, SR-BI and SR-BII (previously known as SR-BI, SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues, SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells, Therefore, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells, 2) are the alternatively spliced products of a single gene, High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
Cav2, 3 BII CACH6 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Scavenger Receptor BII Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Scavenger Receptor BII |
| Short name: |
Scavenger Receptor BII Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Scavenger Receptor BII (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1392 |
| Gene: |
CACNA1E |
More about : CACNA1E |
| Long gene name: |
calcium voltage-gated channel subunit alpha1 E |
| Synonyms gene: |
CACNL1A6 |
| Synonyms gene name: |
R type, alpha 1E subunit calcium voltage-gated channel subunit alpha1 subunit E , calcium channel, voltage-dependent |
| Locus: |
1q25, 3 |
| Discovery year: |
1994-12-20 |
| GenBank acession: |
AK096563 |
| Entrez gene record: |
777 |
| Pubmed identfication: |
8388125 16382099 |
| RefSeq identity: |
NM_000721 |
| Classification: |
Calcium voltage-gated channel subunits EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000037301 |