| Long name: |
Biotin Conjugated, Scavenger Receptor BII Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Scavenger Receptor BII |
| Specificity: |
This is a highly specific antibody against Scavenger Receptor BII |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
222-242/478 |
| Subcellular location: |
Helical |
| Source: |
KLH conjugated synthetic peptide derived from human Scavenger Receptor BII |
| Gene ID number: |
950 |
| Swiss Prot: |
Q14108 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Although the role of these scavenger receptors is not completely clear, Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, SR-BI and SR-BII (previously known as SR-BI, SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues, SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells, Therefore, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells, 2) are the alternatively spliced products of a single gene, High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Cav2, 3 BII CACH6 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Scavenger Receptor BII Conjugated |
| Short name: |
Conjugated, Scavenger Receptor BII Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Scavenger Receptor BII (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1392 |
| Gene: |
CACNA1E |
More about : CACNA1E |
| Long gene name: |
calcium voltage-gated channel subunit alpha1 E |
| Synonyms gene: |
CACNL1A6 |
| Synonyms gene name: |
R type, alpha 1E subunit calcium voltage-gated channel subunit alpha1 subunit E , calcium channel, voltage-dependent |
| Locus: |
1q25, 3 |
| Discovery year: |
1994-12-20 |
| GenBank acession: |
AK096563 |
| Entrez gene record: |
777 |
| Pubmed identfication: |
8388125 16382099 |
| RefSeq identity: |
NM_000721 |
| Classification: |
Calcium voltage-gated channel subunits EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000037301 |