| Long name: |
Scavenger Receptor BII Antibody |
| Also known as: |
Scavenger Receptor BII Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Scavenger Receptor BII |
| Specificity: |
This is a highly specific antibody against Scavenger Receptor BII |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
222-242/478 |
| Subcellular location: |
Helical |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Scavenger Receptor BII |
| Gene ID number: |
950 |
| Swiss Prot: |
Q14108 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Although the role of these scavenger receptors is not completely clear, Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, SR-BI and SR-BII (previously known as SR-BI, SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues, SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells, Therefore, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells, 2) are the alternatively spliced products of a single gene, High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
85 kDa lysosomal membrane sialoglycoprotein, CD36, CD36 antigen-like 2, CD36L2, EPM4, HLGP85, LGP85, LIMP II, LIMP-2, LIMP2, LIMPII, Lysosome membrane protein 2, Lysosome membrane protein II, SCARB2, SR-BII, Scavenger receptor class B member 2, AMRF |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Scavenger Receptor BII |
| Short name: |
Scavenger Receptor BII Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Scavenger Receptor BII (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1392 |
| Gene: |
CACNA1E |
More about : CACNA1E |
| Long gene name: |
calcium voltage-gated channel subunit alpha1 E |
| Synonyms gene: |
CACNL1A6 |
| Synonyms gene name: |
R type, alpha 1E subunit calcium voltage-gated channel subunit alpha1 subunit E , calcium channel, voltage-dependent |
| Synonyms: |
Cav2, 3 BII CACH6 |
| Locus: |
1q25, 3 |
| Discovery year: |
1994-12-20 |
| GenBank acession: |
AK096563 |
| Entrez gene record: |
777 |
| Pubmed identfication: |
8388125 16382099 |
| RefSeq identity: |
NM_000721 |
| Classification: |
Calcium voltage-gated channel subunits EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000037301 |