| Long name: |
Cy5, 5 Conjugated, Scavenger Receptor BII Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Scavenger Receptor BII |
| Specificity: |
This is a highly specific antibody against Scavenger Receptor BII |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
222-242/478 |
| Subcellular location: |
Helical |
| Source: |
KLH conjugated synthetic peptide derived from human Scavenger Receptor BII |
| Gene ID number: |
950 |
| Swiss Prot: |
Q14108 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Although the role of these scavenger receptors is not completely clear, Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, SR-BI and SR-BII (previously known as SR-BI, SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues, SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells, Therefore, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells, 2) are the alternatively spliced products of a single gene, High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
Cav2, 3 BII CACH6 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
Scavenger Receptor BII Conjugated |
| Short name: |
Conjugated, Scavenger Receptor BII Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, Scavenger Receptor BII (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1392 |
| Gene: |
CACNA1E |
More about : CACNA1E |
| Long gene name: |
calcium voltage-gated channel subunit alpha1 E |
| Synonyms gene: |
CACNL1A6 |
| Synonyms gene name: |
R type, alpha 1E subunit calcium voltage-gated channel subunit alpha1 subunit E , calcium channel, voltage-dependent |
| Locus: |
1q25, 3 |
| Discovery year: |
1994-12-20 |
| GenBank acession: |
AK096563 |
| Entrez gene record: |
777 |
| Pubmed identfication: |
8388125 16382099 |
| RefSeq identity: |
NM_000721 |
| Classification: |
Calcium voltage-gated channel subunits EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000037301 |