| Long name: |
ALEXA FLUOR 350 Conjugated, RRM2 Polyclonal Antibody |
| Also known as: |
Anti-RRM2 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RRM2 |
| Specificity: |
This is a highly specific antibody against RRM2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RRM2 |
| Gene ID Number: |
6241 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
It is an enzymatic complex consisting of two nonidentical subunits, R1 and R2, R2, R2 expression is strictly correlated to the S-phase of the cell cycle, R2 is the limiting factor of the catalytic activity of the ribonucleotide reductase enzymatic complex, While R2 seems to be involved solely in the maintenance of dNTPs for DNA replication, a similar protein, has been shown to be responsible for the production of dNTPs in response to DNA damage, is localized to the cytoplasm, p53R2, the smaller subunit, whereas R1 remains constant throughout all phases of the cell cycle, which are inactive separately, Ribonucleotide reductase is essential for the production and maintenance of the level of deoxyribonucleoside triphosphates (dNTPs) required for DNA synthesis |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
RRM2 |
| Short name: |
RRM2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, RRM2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10452 |
| Gene: |
RRM2 |
More about : RRM2 |
| Long gene name: |
ribonucleotide reductase regulatory subunit M2 |
| Synonyms gene name: |
ribonucleotide reductase M2 polypeptide |
| Locus: |
2p25, 1 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
6241 |
| Havana BLAST/BLAT: |
OTTHUMG00000090449 |