| Long name: |
Cy7 Conjugated, RRM2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RRM2 |
| Specificity: |
This is a highly specific antibody against RRM2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human RRM2 |
| Gene ID number: |
6241 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It is an enzymatic complex consisting of two nonidentical subunits, R1 and R2, R2, R2 expression is strictly correlated to the S-phase of the cell cycle, R2 is the limiting factor of the catalytic activity of the ribonucleotide reductase enzymatic complex, While R2 seems to be involved solely in the maintenance of dNTPs for DNA replication, a similar protein, has been shown to be responsible for the production of dNTPs in response to DNA damage, is localized to the cytoplasm, p53R2, the smaller subunit, whereas R1 remains constant throughout all phases of the cell cycle, which are inactive separately, Ribonucleotide reductase is essential for the production and maintenance of the level of deoxyribonucleoside triphosphates (dNTPs) required for DNA synthesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
RRM2 Conjugated |
| Short name: |
Conjugated, RRM2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, RRM2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10452 |
| Gene: |
RRM2 |
More about : RRM2 |
| Long gene name: |
ribonucleotide reductase regulatory subunit M2 |
| Synonyms gene name: |
ribonucleotide reductase M2 polypeptide |
| Locus: |
2p25, 1 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
6241 |
| Havana BLAST/BLAT: |
OTTHUMG00000090449 |