| Long name: |
ALEXA FLUOR 647 Conjugated, CstF-64 Polyclonal Antibody |
| Also known as: |
Anti-CstF-64 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CstF-64 |
| Specificity: |
This is a highly specific antibody against CstF-64 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CSTF2T/CstF-64 |
| Gene ID Number: |
23283 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CstF-64 contains an RNA binding domain and is responsible for the RNA binding activity of CstF, CstF-64 is expressed in all somatic cells and in pre- and postmeiotic, However, The first step, The gene encoding CstF-64 (designated CSTF2) maps to the X chromosome, The increase in CstF-64 concentration during B cell activation switches IgM heavy chain mRNA expression from membrane-bound to secreted forms, a heterotrimer that is composed of three distinct subunits, a large variant of CstF-64, and promotes the germ cell pattern of polyadenylation, but not meiotic, called t CstF-64, endonucleolytic cleavage of polyadenylation substrates, germ cells, is abundantly expressed in meiotic and postmeiotic cells in the testis and to a lesser extent in the brain, requires CstF (cleavage stimulation factor), suggesting that CstF-64 plays a key role in regulating IgM heavy chain expression during B cell differentiation, whereas t CstF-64 is encoded by an autosomal gene, Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
CstF-64 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the CstF-64 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
CstF-64 |
| Short name: |
CstF-64 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, CstF-64 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2484 |
| Gene: |
CSTF2 |
More about : CSTF2 |
| Long gene name: |
cleavage stimulation factor subunit 2 |
| Synonyms gene name: |
3', 3', 64kD cleavage stimulation factor, cleavage stimulation factor, pre-RNA, pre-RNA, subunit 2, subunit 2 |
| Locus: |
Xq22, 1 |
| Discovery year: |
1994-12-12 |
| GenBank acession: |
BC017712 |
| Entrez gene record: |
1478 |
| Pubmed identfication: |
1741396 |
| RefSeq identity: |
NM_001325 |
| Classification: |
RNA binding motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000022709 |
| Locus Specific Databases: |
Mental Retardation database |