| Catalog number: | bs-6995R-A555 |
|---|---|
| Price: | 332 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | CstF-64 Antibody, ALEXA FLUOR 555 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 555 Conjugated, CstF-64 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-CstF-64 PAb ALEXA FLUOR 555 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 555, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | CstF-64 |
| Specificity: | This is a highly specific antibody against CstF-64 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CSTF2T/CstF-64 |
| Gene ID Number: | 23283 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | CstF-64 contains an RNA binding domain and is responsible for the RNA binding activity of CstF, CstF-64 is expressed in all somatic cells and in pre- and postmeiotic, However, The first step, The gene encoding CstF-64 (designated CSTF2) maps to the X chromosome, The increase in CstF-64 concentration during B cell activation switches IgM heavy chain mRNA expression from membrane-bound to secreted forms, a heterotrimer that is composed of three distinct subunits, a large variant of CstF-64, and promotes the germ cell pattern of polyadenylation, but not meiotic, called t CstF-64, endonucleolytic cleavage of polyadenylation substrates, germ cells, is abundantly expressed in meiotic and postmeiotic cells in the testis and to a lesser extent in the brain, requires CstF (cleavage stimulation factor), suggesting that CstF-64 plays a key role in regulating IgM heavy chain expression during B cell differentiation, whereas t CstF-64 is encoded by an autosomal gene, Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 553nm/568nm |
| Synonyms: | CstF-64 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 555, Alexa Fluor |
| Gene target: | CstF-64 |
| Short name: | CstF-64 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 555 |
| Alternative name: | ALEXA FLUOR 555, CstF-64 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 2484 |
| Gene: | CSTF2 | More about : CSTF2 |
| Long gene name: | cleavage stimulation factor subunit 2 |
| Synonyms gene name: | 3', 3', 64kD cleavage stimulation factor, cleavage stimulation factor, pre-RNA, pre-RNA, subunit 2, subunit 2 |
| Locus: | Xq22, 1 |
| Discovery year: | 1994-12-12 |
| GenBank acession: | BC017712 |
| Entrez gene record: | 1478 |
| Pubmed identfication: | 1741396 |
| RefSeq identity: | NM_001325 |
| Classification: | RNA binding motif containing |
| Havana BLAST/BLAT: | OTTHUMG00000022709 |
| Locus Specific Databases: | Mental Retardation database |
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