| Long name: |
FITC Conjugated, CCDC98 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCDC98 |
| Specificity: |
This is a highly specific antibody against CCDC98 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
85-135/409 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human CCDC98 |
| Gene ID number: |
84142 |
| Swiss Prot: |
Q6UWZ7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Component of the BRCA1-A complex, The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs, Involved in DNA damage response and double-strand break (DSB) repair |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FLJ13614 ABRA1 ABRAXAS |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CCDC98 Conjugated |
| Short name: |
FITC Conjugated, CCDC98 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CCDC98 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
25829 |
| Gene: |
FAM175A |
More about : FAM175A |
| Long gene name: |
family with sequence similarity 175 member A |
| Synonyms gene: |
CCDC98 |
| Synonyms gene name: |
coiled-coil domain containing 98 family with sequence similarity 175, member A |
| Synonyms name: |
Abraxas protein |
| Locus: |
4q21, 23 |
| Discovery year: |
2006-04-03 |
| GenBank acession: |
AK023676 |
| Entrez gene record: |
84142 |
| Pubmed identfication: |
12975309 17525340 |
| RefSeq identity: |
NM_139076 |
| Classification: |
BRCA1 A complex |
| Havana BLAST/BLAT: |
OTTHUMG00000130429 |