| Long name: |
Cy5, 5 Conjugated, CCDC98 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCDC98 |
| Specificity: |
This is a highly specific antibody against CCDC98 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
85-135/409 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human CCDC98 |
| Gene ID number: |
84142 |
| Swiss Prot: |
Q6UWZ7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Component of the BRCA1-A complex, The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs, Involved in DNA damage response and double-strand break (DSB) repair |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
FLJ13614 ABRA1 ABRAXAS |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
CCDC98 Conjugated |
| Short name: |
Conjugated, CCDC98 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, CCDC98 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
25829 |
| Gene: |
FAM175A |
More about : FAM175A |
| Long gene name: |
family with sequence similarity 175 member A |
| Synonyms gene: |
CCDC98 |
| Synonyms gene name: |
coiled-coil domain containing 98 family with sequence similarity 175, member A |
| Synonyms name: |
Abraxas protein |
| Locus: |
4q21, 23 |
| Discovery year: |
2006-04-03 |
| GenBank acession: |
AK023676 |
| Entrez gene record: |
84142 |
| Pubmed identfication: |
12975309 17525340 |
| RefSeq identity: |
NM_139076 |
| Classification: |
BRCA1 A complex |
| Havana BLAST/BLAT: |
OTTHUMG00000130429 |