| Long name: |
ALEXA FLUOR 488 Conjugated, CCDC98 Polyclonal Antibody |
| Also known as: |
Anti-CCDC98 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCDC98 |
| Specificity: |
This is a highly specific antibody against CCDC98 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
85-135/409 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CCDC98 |
| Gene ID Number: |
84142 |
| Swiss Prot: |
Q6UWZ7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Component of the BRCA1-A complex, The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs, Involved in DNA damage response and double-strand break (DSB) repair |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
FLJ13614 ABRA1 ABRAXAS |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CCDC98 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CCDC98 |
| Short name: |
CCDC98 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, CCDC98 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
25829 |
| Gene: |
FAM175A |
More about : FAM175A |
| Long gene name: |
family with sequence similarity 175 member A |
| Synonyms gene: |
CCDC98 |
| Synonyms gene name: |
coiled-coil domain containing 98 family with sequence similarity 175, member A |
| Synonyms name: |
Abraxas protein |
| Locus: |
4q21, 23 |
| Discovery year: |
2006-04-03 |
| GenBank acession: |
AK023676 |
| Entrez gene record: |
84142 |
| Pubmed identfication: |
12975309 17525340 |
| RefSeq identity: |
NM_139076 |
| Classification: |
BRCA1 A complex |
| Havana BLAST/BLAT: |
OTTHUMG00000130429 |