| Long name: |
Biotin Conjugated, CCDC98 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCDC98 |
| Specificity: |
This is a highly specific antibody against CCDC98 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
85-135/409 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human CCDC98 |
| Gene ID number: |
84142 |
| Swiss Prot: |
Q6UWZ7 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Component of the BRCA1-A complex, The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs, Involved in DNA damage response and double-strand break (DSB) repair |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
FLJ13614 ABRA1 ABRAXAS |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CCDC98 Conjugated |
| Short name: |
Conjugated, CCDC98 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, CCDC98 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
25829 |
| Gene: |
FAM175A |
More about : FAM175A |
| Long gene name: |
family with sequence similarity 175 member A |
| Synonyms gene: |
CCDC98 |
| Synonyms gene name: |
coiled-coil domain containing 98 family with sequence similarity 175, member A |
| Synonyms name: |
Abraxas protein |
| Locus: |
4q21, 23 |
| Discovery year: |
2006-04-03 |
| GenBank acession: |
AK023676 |
| Entrez gene record: |
84142 |
| Pubmed identfication: |
12975309 17525340 |
| RefSeq identity: |
NM_139076 |
| Classification: |
BRCA1 A complex |
| Havana BLAST/BLAT: |
OTTHUMG00000130429 |