| Long name: |
ALEXA FLUOR 350 Conjugated, OSBP2 Polyclonal Antibody |
| Also known as: |
Anti-OSBP2 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OSBP2 |
| Specificity: |
This is a highly specific antibody against OSBP2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OSBP2 |
| Gene ID Number: |
23762 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
HMG-CoA reductase and the low density lipoprotein receptor (LDLR), OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), OSBP localizes to the cytosol and is widely expressed, OSBPs are involved in lipid metabolism and signal transduction, The OSBP protein transports sterols from lysosomes to the nucleus, The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties, a suppressor of cholesterol synthesis gene transcription in cultured cells, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols, as well as vesicle transport, retina and fetal liver, where sterols downregulate the genes for HMG synthetase, which share a high overall similarity, while OSBP2 is mainly detected in testis, The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
KIAA1664 ORP-4 ORP4 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
OSBP2 |
| Short name: |
OSBP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, OSBP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8504 |
| Gene: |
OSBP2 |
More about : OSBP2 |
| Long gene name: |
oxysterol binding protein 2 |
| Synonyms gene: |
OSBPL1 |
| Locus: |
22q12, 2 |
| Discovery year: |
1999-10-29 |
| Entrez gene record: |
23762 |
| Pubmed identfication: |
10591208 11278871 11802775 |
| RefSeq identity: |
NM_030758 |
| Classification: |
Pleckstrin homology domain containing Oxysterol binding proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000151153 |