| Long name: |
Cy7 Conjugated, IGF-I Receptor beta Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IGF-I Receptor beta |
| Specificity: |
This is a highly specific antibody against IGF-I Receptor beta |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human IGF-IR beta chain |
| Gene ID number: |
3480 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Cleavage of the precursor generates alpha and beta subunits, It has tyrosine kinase activity, It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival, Jul 2008], The insulin-like growth factor I receptor plays a critical role in transformation events, [provided by RefSeq, This receptor binds insulin-like growth factor with a high affinity |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
CD221, CD221 antigen, IGF 1 receptor, IGF 1R, IGF I receptor, IGF I receptor beta, IGF1 Receptor, IGF1R, IGF1R beta, IGF1R_HUMAN, IGFIR, IGFIR beta, IGFIRC, Insulin like growth factor 1 receptor, Insulin like growth factor 1 receptor beta, Insulin like growth factor 1 receptor precursor, JTK13, MGC142170, MGC142172, GF 1R beta |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Description: |
IGF-1 acts via specific receptor, IGF-1R, IGF-II, Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver, Raf/Ras and PI3K cascades, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells, IGF-I |
| Gene target: |
I Receptor beta Conjugated |
| Short name: |
Conjugated, IGF-I Receptor beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, igfs, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, IGF-I Receptor b (Antibody to) |
| Alternative technique: |
antibodies |