| Long name: |
ALEXA FLUOR 647 Conjugated, IGF-I Receptor beta Polyclonal Antibody |
| Also known as: |
Anti-IGF-I Receptor beta PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IGF-I Receptor beta |
| Specificity: |
This is a highly specific antibody against IGF-I Receptor beta |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IGF-IR beta chain |
| Gene ID Number: |
3480 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Cleavage of the precursor generates alpha and beta subunits, It has tyrosine kinase activity, It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival, Jul 2008], The insulin-like growth factor I receptor plays a critical role in transformation events, [provided by RefSeq, This receptor binds insulin-like growth factor with a high affinity |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
ALK-5 ACVRLK4 ALK5 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the IGF-I Receptor beta Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Description: |
IGF-1 acts via specific receptor, IGF-1R, IGF-II, Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver, Raf/Ras and PI3K cascades, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells, IGF-I |
| Gene target: |
I Receptor beta |
| Short name: |
IGF-I Receptor beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, igfs, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, IGF-I Receptor b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11772 |
| Gene: |
TGFBR1 |
More about : TGFBR1 |
| Long gene name: |
transforming growth factor beta receptor 1 |
| Synonyms gene: |
MSSE ESS1 |
| Synonyms gene name: |
multiple self-healing squamous epithelioma transforming growth factor beta receptor I |
| Synonyms name: |
53kDa , activin A receptor type II-like kinase |
| Locus: |
9q22, 33 |
| Discovery year: |
1993-09-30 |
| Entrez gene record: |
7046 |
| Pubmed identfication: |
1319842 8530052 21358634 |
| Classification: |
Type 1 receptor serine/threonine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000020353 |
| Locus Specific Databases: |
Belgium , Ghent, LOVD - Center for Medical Genetics |