| Long name: |
ALEXA FLUOR 555 Conjugated, RAB5 Polyclonal Antibody |
| Also known as: |
Anti-RAB5 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RAB5 |
| Specificity: |
This is a highly specific antibody against RAB5 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RAB5 |
| Gene ID Number: |
5868 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CXC, Due to the presence of truncated sequences in this CD, GTPase activating proteins (GAPs) interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP, Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state, In mammals, In yeast, Lipid binding is essential for membrane attachment, Most Rab GTPases contain a lipid modification site at the C-terminus, Rab5 GTPases localize to early endosomes and regulate fusion of clathrin-coated vesicles to early endosomes and fusion between early endosomes, Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), The members of this subfamily are involved in endocytosis and endocytic-sorting pathways, This subfamily includes Rab5 and Rab22 of mammals, Ypt51/Ypt52/Ypt53 of yeast, Ypt51p family members similarly regulate membrane trafficking through prevacuolar compartments, a key feature of most Rab proteins, and RabF of plants, or CCX, the lipid modification site is not available for annotation, which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization, with sequence motifs CC, Rab5-related subfamily |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
RAB5 |
| Short name: |
RAB5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, RAB5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9783 |
| Gene: |
RAB5A |
More about : RAB5A |
| Long gene name: |
RAB5A, member RAS oncogene family |
| Synonyms gene: |
RAB5 |
| Synonyms name: |
RAS-associated protein RAB5A |
| Locus: |
3p24, 3 |
| Discovery year: |
1990-01-22 |
| Entrez gene record: |
5868 |
| Pubmed identfication: |
1999336 |
| RefSeq identity: |
NM_004162 |
| Classification: |
RAB, member RAS oncogene GTPases |
| Havana BLAST/BLAT: |
OTTHUMG00000129889 |