| Long name: |
RAB5 Primary Polyclonal Antibody |
| Also known as: |
RAB5 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RAB5 |
| Specificity: |
This is a highly specific antibody against RAB5 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RAB5 |
| Gene ID number: |
5868 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CXC, Due to the presence of truncated sequences in this CD, GTPase activating proteins (GAPs) interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP, Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state, In mammals, In yeast, Lipid binding is essential for membrane attachment, Most Rab GTPases contain a lipid modification site at the C-terminus, Rab5 GTPases localize to early endosomes and regulate fusion of clathrin-coated vesicles to early endosomes and fusion between early endosomes, Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), The members of this subfamily are involved in endocytosis and endocytic-sorting pathways, This subfamily includes Rab5 and Rab22 of mammals, Ypt51/Ypt52/Ypt53 of yeast, Ypt51p family members similarly regulate membrane trafficking through prevacuolar compartments, a key feature of most Rab proteins, and RabF of plants, or CCX, the lipid modification site is not available for annotation, which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization, with sequence motifs CC, Rab5-related subfamily |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
RAB 5A, RAB5A, RAB5A member RAS oncogene family, RAB5A_HUMAN, RAS associated protein RAB5A, Ras related protein Rab 5A, Ras-related protein Rab-5A, RAB 5 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RAB5 |
| Short name: |
RAB5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAB5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9783 |
| Gene: |
RAB5A |
More about : RAB5A |
| Long gene name: |
RAB5A, member RAS oncogene family |
| Synonyms gene: |
RAB5 |
| Synonyms name: |
RAS-associated protein RAB5A |
| Locus: |
3p24, 3 |
| Discovery year: |
1990-01-22 |
| Entrez gene record: |
5868 |
| Pubmed identfication: |
1999336 |
| RefSeq identity: |
NM_004162 |
| Classification: |
RAB, member RAS oncogene GTPases |
| Havana BLAST/BLAT: |
OTTHUMG00000129889 |