| Long name: |
Cy5 Conjugated, WAVE 1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
WAVE 1 |
| Specificity: |
This is a highly specific antibody against WAVE 1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human WAVE 1 |
| Gene ID number: |
8936 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating Actin reorganization downstream of the Rho family of small GTPases, The protein homologs WAVE1 and WAVE2 regulate membrane ruffling by inducing the formation of Actin filament clusters in response to GTP binding and by activating Rac, They mediate Actin polymerization by cooperating with the Arp2/3 complex, WAVE1, WAVE3 forms a multiprotein complex that links receptor kinases with Actin and plays a role in the transduction of signals involving changes in cell shape, function or motility, is expressed primarily in the brain, thereby promoting the formation of Actin filaments, which accumulate at focal adhesions and are also involved in the regulation of the Actin cytoskeleton, which is also designated SCAR (suppressor of cAR), while WAVE2 is widely expressed, with the expression highest in peripheral blood leukocytes, WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in Actin polymerization and cytoskeletal organization |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
WAVE1 SCAR1 KIAA0269 WAVE |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
WAVE 1 Conjugated |
| Short name: |
Conjugated, WAVE 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, WAVE 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12732 |
| Gene: |
WASF1 |
More about : WASF1 |
| Long gene name: |
WAS protein family member 1 |
| Synonyms gene name: |
WAS protein family, member 1 |
| Locus: |
6q21 |
| Discovery year: |
1999-09-21 |
| GenBank acession: |
D87459 |
| Entrez gene record: |
8936 |
| Pubmed identfication: |
9843499 9889097 |
| RefSeq identity: |
NM_003931 |
| Classification: |
A-kinase anchoring proteins Wiskott-Aldrich Syndrome protein family |
| Havana BLAST/BLAT: |
OTTHUMG00000015357 |