| Long name: |
ALEXA FLUOR 647 Conjugated, WAVE 1 Polyclonal Antibody |
| Also known as: |
Anti-WAVE 1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
WAVE 1 |
| Specificity: |
This is a highly specific antibody against WAVE 1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WAVE 1 |
| Gene ID Number: |
8936 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating Actin reorganization downstream of the Rho family of small GTPases, The protein homologs WAVE1 and WAVE2 regulate membrane ruffling by inducing the formation of Actin filament clusters in response to GTP binding and by activating Rac, They mediate Actin polymerization by cooperating with the Arp2/3 complex, WAVE1, WAVE3 forms a multiprotein complex that links receptor kinases with Actin and plays a role in the transduction of signals involving changes in cell shape, function or motility, is expressed primarily in the brain, thereby promoting the formation of Actin filaments, which accumulate at focal adhesions and are also involved in the regulation of the Actin cytoskeleton, which is also designated SCAR (suppressor of cAR), while WAVE2 is widely expressed, with the expression highest in peripheral blood leukocytes, WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in Actin polymerization and cytoskeletal organization |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
WAVE1 SCAR1 KIAA0269 WAVE |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the WAVE 1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
WAVE 1 |
| Short name: |
WAVE 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, WAVE 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12732 |
| Gene: |
WASF1 |
More about : WASF1 |
| Long gene name: |
WAS protein family member 1 |
| Synonyms gene name: |
WAS protein family, member 1 |
| Locus: |
6q21 |
| Discovery year: |
1999-09-21 |
| GenBank acession: |
D87459 |
| Entrez gene record: |
8936 |
| Pubmed identfication: |
9843499 9889097 |
| RefSeq identity: |
NM_003931 |
| Classification: |
A-kinase anchoring proteins Wiskott-Aldrich Syndrome protein family |
| Havana BLAST/BLAT: |
OTTHUMG00000015357 |