| Long name: |
WAVE 1 Primary Polyclonal Antibody |
| Also known as: |
WAVE 1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
WAVE 1 |
| Specificity: |
This is a highly specific antibody against WAVE 1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WAVE 1 |
| Gene ID number: |
8936 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating Actin reorganization downstream of the Rho family of small GTPases, The protein homologs WAVE1 and WAVE2 regulate membrane ruffling by inducing the formation of Actin filament clusters in response to GTP binding and by activating Rac, They mediate Actin polymerization by cooperating with the Arp2/3 complex, WAVE1, WAVE3 forms a multiprotein complex that links receptor kinases with Actin and plays a role in the transduction of signals involving changes in cell shape, function or motility, is expressed primarily in the brain, thereby promoting the formation of Actin filaments, which accumulate at focal adhesions and are also involved in the regulation of the Actin cytoskeleton, which is also designated SCAR (suppressor of cAR), while WAVE2 is widely expressed, with the expression highest in peripheral blood leukocytes, WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in Actin polymerization and cytoskeletal organization |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Protein WAVE1, SCAR1, Similar to a plant extensin like protein, Verprolin homology domain containing protein 1, Verprolin homology domain-containing protein 1, WAS protein family, WASF1_HUMAN, WASL, WASP family 1, WASP family protein member 1, WAVE, WAVE1, Wasf1, Wiskott Aldrich syndrome protein family member 1, Wiskott-Aldrich syndrome protein family member 1, member 1, Protein WAVE-1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
WAVE 1 |
| Short name: |
WAVE 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
WAVE 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12732 |
| Gene: |
WASF1 |
More about : WASF1 |
| Long gene name: |
WAS protein family member 1 |
| Synonyms gene name: |
WAS protein family, member 1 |
| Synonyms: |
WAVE1 SCAR1 KIAA0269 WAVE |
| Locus: |
6q21 |
| Discovery year: |
1999-09-21 |
| GenBank acession: |
D87459 |
| Entrez gene record: |
8936 |
| Pubmed identfication: |
9843499 9889097 |
| RefSeq identity: |
NM_003931 |
| Classification: |
A-kinase anchoring proteins Wiskott-Aldrich Syndrome protein family |
| Havana BLAST/BLAT: |
OTTHUMG00000015357 |