| Catalog number: | bs-5591R-A594 |
|---|---|
| Price: | 536 € |
| Supplier: | MBS mono |
| Product name: | YES1 (Tyr426) Antibody, ALEXA FLUOR 594 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 594 Conjugated, YES1 (Tyr426) Polyclonal Antibody |
|---|---|
| Also known as: | Anti-YES1 Tyr426 PAb ALEXA FLUOR 594 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 594, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | YES1 Tyr426 |
| Specificity: | This is a highly specific antibody against YES1 Tyr426 |
| Modification: | Phosphorylation |
| Modification Site: | Tyr426 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 420-430/543 |
| Subcellular location: | Cytoplasm |
| Source: | KLH conjugated synthetic phosphopeptide derived from human YES1 around the phosphorylation site of Tyr426 |
| Gene ID Number: | 7525 |
| Swiss Prot: | P07947 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Also involved in G2/M progression and cytokinesis, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, PDGFR, Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration, Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts, Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase, Stimulation by receptor tyrosine kinases (RTKs) including EGRF, Upon EGFR activation, Upon T-cell stimulation by CXCL12, and activation and phosphorylation of downstream substrates, and differentiation, apoptosis, cell-cell adhesion, cytoskeleton remodeling, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly, Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 590nm/617nm |
| Synonyms: | Yes c-yes HsT441 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: | Alexa conjugate 1 |
| Gene target: | YES1 (Tyr426) |
| Short name: | YES1 (Tyr426) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 594 |
| Alternative name: | ALEXA FLUOR 594, YES1 (Tyr426) (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 12841 |
| Gene: | YES1 | More about : YES1 |
| Long gene name: | Src family tyrosine kinase , YES proto-oncogene 1 |
| Synonyms gene name: | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 |
| Locus: | 18p11, 32 |
| Discovery year: | 1986-01-01 |
| GenBank acession: | M15990 |
| Entrez gene record: | 7525 |
| Pubmed identfication: | 2983418 |
| RefSeq identity: | NM_005433 |
| Classification: | SH2 domain containing Src family tyrosine kinases |
| Havana BLAST/BLAT: | OTTHUMG00000131472 |
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| bs-5591R-Cy5 | YES1 (Tyr426) Antibody, Cy5 Conjugated | 0.1ml | 368 € | Bioss Primary Conjugated Antibodies | human |
| bs-5591R-Cy5.5 | YES1 (Tyr426) Antibody, Cy5.5 Conjugated | 0.1ml | 368 € | Bioss Primary Conjugated Antibodies | human |
| bs-5591R-Cy7 | YES1 (Tyr426) Antibody, Cy7 Conjugated | 0.1ml | 368 € | Bioss Primary Conjugated Antibodies | human |
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