| Catalog number: | bs-5324R-A350 |
|---|---|
| Price: | Ask price € |
| Supplier: | accurate-monoclonals |
| Product name: | CD95 (Tyr232) Antibody, ALEXA FLUOR 350 |
| Quantity: | vial |
| Related search: |
| Long name: | ALEXA FLUOR 350 Conjugated, CD95 (Tyr232) Polyclonal Antibody |
|---|---|
| Also known as: | Anti-CD95 Tyr232 PAb ALEXA FLUOR 350 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 350, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | CD95 Tyr232 |
| Specificity: | This is a highly specific antibody against CD95 Tyr232 |
| Modification: | Phosphorylation |
| Modification Site: | Tyr232 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 210-240/335 |
| Subcellular location: | Intracellular |
| Source: | KLH conjugated synthetic phosphopeptide derived from human FAS around the phosphorylation site of Tyr232 |
| Gene ID Number: | 355 |
| Swiss Prot: | P25445 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, The adapter molecule FADD recruits caspase-8 to the activated receptor, The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis, The secreted isoforms 2 to 6 block apoptosis (in vitro), in the antigen-stimulated suicide of mature T-cells, or both, Receptor for TNFSF6/FASLG |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 343nm/442nm |
| Synonyms: | CD95 APO-1 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 350, Alexa Fluor |
| Gene target: | CD95 (Tyr232) |
| Short name: | CD95 (Tyr232) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 350 |
| Alternative name: | ALEXA FLUOR 350, CD95 (Tyr232) (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 11920 |
| Gene: | FAS | More about : FAS |
| Long gene name: | Fas cell surface death receptor |
| Synonyms gene: | FAS1 APT1 TNFRSF6 |
| Synonyms gene name: | member 6 Fas (TNF receptor superfamily, member 6) , tumor necrosis factor receptor superfamily |
| Synonyms name: | TNF receptor superfamily member 6 |
| Locus: | 10q23, 31 |
| Discovery year: | 1992-06-25 |
| GenBank acession: | M67454 |
| Entrez gene record: | 355 |
| Pubmed identfication: | 1385299 1385309 |
| Classification: | CD molecules Tumor necrosis factor receptor superfamily Death inducing signaling complex |
| Havana BLAST/BLAT: | OTTHUMG00000018701 |
| Locus Specific Databases: | Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS LOVD at NCBI LRG_134 |
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