CD95 (Tyr232) Antibody

Catalog number:	bs-5324R Buy Now
Price:	509 €
Supplier:	MBS Polyclonals
Product name:	CD95 (Tyr232) Antibody
Quantity:	500ug
Related search:	receptor gene antibodies superfamily synonyms factor signaling

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Long name:	CD95 (Tyr232) Primary Polyclonal Antibody
Also known as:	CD95 (Tyr232) PAb
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	CD95 Tyr232
Specificity:	This is a highly specific antibody against CD95 Tyr232
Modification(s):	Phosphorylation
Modification site(s):	Tyr232
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	210-240/335
Subcellular location:	Intracellular
Source:	KLH conjugated synthetic phosphopeptide derived from human FAS around the phosphorylation site of Tyr232
Gene ID number:	355
Swiss Prot:	P25445
Tested Applications:	IF(IHC-P), IHC-P, WB
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity:	Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, The adapter molecule FADD recruits caspase-8 to the activated receptor, The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis, The secreted isoforms 2 to 6 block apoptosis (in vitro), in the antigen-stimulated suicide of mature T-cells, or both, Receptor for TNFSF6/FASLG
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	ALPS1A, APO-1, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6, Tumor necrosis factor receptor superfamily member 6, APT1
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	CD95 (Tyr232)
Short name:	CD95 (Tyr232) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	CD95 (Tyr232) (Antibody to)
Alternative technique:	antibodies
Identity:	11920
Gene:	FAS | More about : FAS
Long gene name:	Fas cell surface death receptor
Synonyms gene:	FAS1 APT1 TNFRSF6
Synonyms gene name:	member 6 Fas (TNF receptor superfamily, member 6) , tumor necrosis factor receptor superfamily
Synonyms:	CD95 APO-1
Synonyms name:	TNF receptor superfamily member 6
Locus:	10q23, 31
Discovery year:	1992-06-25
GenBank acession:	M67454
Entrez gene record:	355
Pubmed identfication:	1385299 1385309
Classification:	CD molecules Tumor necrosis factor receptor superfamily Death inducing signaling complex
Havana BLAST/BLAT:	OTTHUMG00000018701
Locus Specific Databases:	Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS LOVD at NCBI LRG_134

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