| Long name: |
Erk1/2 (Phospho-Thr202/Tyr204) Primary Polyclonal Antibody |
| Also known as: |
Erk1/2 (Phospho-Thr202/Tyr204) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Erk1/2 (Phospho-Thr202/Tyr204) |
| Specificity: |
This is a highly specific antibody against Erk1/2 (Phospho-Thr202/Tyr204) |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Thr202/Tyr204 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Source: |
Synthetic phospho-peptide |
| Gene ID number: |
5595 |
| Swiss Prot: |
P27361 |
| Tested Applications: |
WB |
| Recommended dilutions: |
000), WB (1:2 |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
MEK1/2, Many different stimuli, Once actived, Raf phosphorylates serine residue in 2 further kinases, Ras interacts with Raf, Upon activation, When growth factors bind to the receptor tyrosine kinase, activate the ERK1 and ERK2 pathways, and postmitotic functions in differentiated cells, cytokines, including growth factors, ligands for heterotrimeric guanine nucleotidebinding protein (G protein)-coupled receptors and transforming agents, mitosis, the ERKs either phosphorylate a number of cytoplasmic targets or migrate to the nucleus, the serine/threonine protein kinase and activates it as well, virus infection, where they phosphorylate and activate a number of transcription factors such as c-Fos and Elk-1, which in turn phosphorylates tyrosine/threonine in extracellular-signal regulated kinase(ERK) 1/2, ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ERK-1, ERT2, Extracellular signal-regulated kinase 1, HS44KDAP, HUMKER1A, Insulin-stimulated MAP2 kinase, MAP kinase 3, MAP kinase isoform p44, MAPK 3, MAPK3, Microtubule-associated protein 2 kinase, Mitogen-activated protein kinase 3, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK, ERK1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Erk1/2 (Phospho-Thr202/Tyr204) |
| Short name: |
Erk1/2 (Phospho-Thr202/Tyr204) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Erk1/2 (phosphorilated-Thr202/Tyr204) (Antibody to) |
| Alternative technique: |
antibodies |