| Long name: |
HRP Conjugated, ERK1/2(Thr202 + Tyr204) Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ERK1/2 Thr202 + Tyr204 |
| Specificity: |
This is a highly specific antibody against ERK1/2 Thr202 + Tyr204 |
| Modification: |
Phosphorylation |
| Modification site: |
Thr202 + Tyr204 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
196-210/379 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human p44/42 MAPK around the phosphorylation site of (Thr202/Tyr204) |
| Gene ID number: |
5595 |
| Swiss Prot: |
P27361 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Bovine, Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Cell stimulation induces the activation of a signaling cascade, ERK (extracellular signal regulated kinase), ERK1 and ERK2 are phosphorylated within the activation loop on both a Threonine and a Tyrosine residue (within a Thr-Glu-Tyr motif) by MEKs (MAPK/ERK kinases), These kinases belong to a family of serine/threonine kinases that are activated upon treatment of cells with a large variety of stimuli including mitogens, also known as MAPK (mitogen activated protein kinase) has two closely related isoforms of 44 kDa and 42 kDa, and bioactive peptides, cytokines, growth factors, hormones, respectively, the downstream effects of which have been linked to the regulation of cell growth and differentiation as well as the cytoskeleton, thereby greatly elevating the activity of ERK1&, 2, p44/42 MAP Kinase(Thr202) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
ERK1 p44mapk p44erk1 |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
ERK1/2(Thr202 + Tyr204) Conjugated |
| Short name: |
Conjugated, ERK1/2(Thr202 + Tyr204) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, ERK1/2(Thr202 and Tyr204) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6877 |
| Gene: |
MAPK3 |
More about : MAPK3 |
| Long gene name: |
mitogen-activated protein kinase 3 |
| Synonyms gene: |
PRKM3 |
| Locus: |
16p11, 2 |
| Discovery year: |
1993-11-05 |
| GenBank acession: |
M84490 |
| Entrez gene record: |
5595 |
| Pubmed identfication: |
9628824 |
| Classification: |
Mitogen-activated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000132149 |