| Long name: |
ALEXA FLUOR 647 Conjugated, CARM1 Polyclonal Antibody |
| Also known as: |
Anti-CARM1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CARM1 |
| Specificity: |
This is a highly specific antibody against CARM1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
430-480/608 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CARM1 |
| Gene ID Number: |
10498 |
| Swiss Prot: |
Q86X55 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts as coactivator for PPARG, Also methylates arginine residues in RNA-binding proteins PABPC1, Also seems to be involved in p53/TP53 transcriptional activation, During monocyte inflammatory stimulation, During myogenic transcriptional activation, During nuclear hormone receptor activation and TCF7L2/TCF4 activation, ELAVL1 and ELAV4, Methylates EP300/P300, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription, Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors, Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, acts together with EP300/P300 as a coactivator for NF-kappa-B, acts together with NCOA3/ACTR as a coactivator for MEF2C, and at 'Arg-580' and 'Arg-604' in the KIX domain, and mRNA stability, both at 'Arg-2142', forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling, methylates histone H3 at 'Arg-17' (H3R17me), pre-mRNA splicing, promotes adipocyte differentiation and the accumulation of brown fat tissue, transcription regulation, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs, which may loosen its interaction with NCOA2/GRIP1, Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
PRMT4 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the CARM1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
CARM1 |
| Short name: |
CARM1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, CARM1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
23393 |
| Gene: |
CARM1 |
More about : CARM1 |
| Long gene name: |
coactivator associated arginine methyltransferase 1 |
| Locus: |
19p13, 2 |
| Discovery year: |
2003-11-14 |
| GenBank acession: |
AF055027 |
| Entrez gene record: |
10498 |
| Pubmed identfication: |
10381882 11724789 |
| RefSeq identity: |
NM_199141 |
| Classification: |
Protein arginine methyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000180699 |