| Long name: |
ALEXA FLUOR 594 Conjugated, MO25 alpha/CAB39 Polyclonal Antibody |
| Also known as: |
Anti-MO25 alpha/CAB39 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MO25 alpha/CAB39 |
| Specificity: |
This is a highly specific antibody against MO25 alpha/CAB39 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MO25 alpha/CAB39 |
| Gene ID Number: |
51719 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CAB39 binds directly to a conserved Trp-Glu-Phe sequence at the STRAD alpha C terminus, CAB39) is a 40-kDa protein that, LKB1-STRAD-MO25 activity is not increased by muscle contraction, Skeletal muscle contraction results in the phosphorylation and activation of the AMP-activated protein kinase (AMPK) by an upstream kinase (AMPKK), The LKB1-STE-related adaptor (STRAD)-mouse protein 25 (MO25) complex is the major AMPKK in skeletal muscle, The latter is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS), This relationship suggests that phosphorylation of AMPK by LKB1-STRAD-MO25 during skeletal muscle contraction may be regulated by allosteric mechanisms, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase, however, markedly enhancing binding of STRAD alpha to LKB1 and increasing LKB1 catalytic activity, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, Mouse protein 25 alpha (MO25 alpha |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CGI-66 MO25 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
MO25 alpha/CAB39 |
| Short name: |
MO25 alpha/CAB39 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, MO25 a/CAB39 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
20292 |
| Gene: |
CAB39 |
More about : CAB39 |
| Long gene name: |
calcium binding protein 39 |
| Locus: |
2q37, 1 |
| Discovery year: |
2004-07-02 |
| GenBank acession: |
AF113536 |
| Entrez gene record: |
51719 |
| RefSeq identity: |
NM_016289 |
| Havana BLAST/BLAT: |
OTTHUMG00000133220 |