| Catalog number: | bs-3636R |
|---|---|
| Price: | 659 € |
| Supplier: | acr |
| Product name: | MO25 alpha/CAB39 Antibody |
| Quantity: | 0,1 mg |
| Related search: |
| Long name: | MO25 alpha/CAB39 Primary Polyclonal Antibody |
|---|---|
| Also known as: | MO25 alpha/CAB39 PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | MO25 alpha/CAB39 |
| Specificity: | This is a highly specific antibody against MO25 alpha/CAB39 |
| Modification(s): | None |
| Modification site(s): | Unmodified antibody |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MO25 alpha/CAB39 |
| Gene ID number: | 51719 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | CAB39 binds directly to a conserved Trp-Glu-Phe sequence at the STRAD alpha C terminus, CAB39) is a 40-kDa protein that, LKB1-STRAD-MO25 activity is not increased by muscle contraction, Skeletal muscle contraction results in the phosphorylation and activation of the AMP-activated protein kinase (AMPK) by an upstream kinase (AMPKK), The LKB1-STE-related adaptor (STRAD)-mouse protein 25 (MO25) complex is the major AMPKK in skeletal muscle, The latter is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS), This relationship suggests that phosphorylation of AMPK by LKB1-STRAD-MO25 during skeletal muscle contraction may be regulated by allosteric mechanisms, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase, however, markedly enhancing binding of STRAD alpha to LKB1 and increasing LKB1 catalytic activity, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, Mouse protein 25 alpha (MO25 alpha |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | CGI 66, CGI66, Calcium binding protein 39, MO25, MO25 alpha, Mouse protein 25 alpha, Protein Mo25, CAB39 |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | MO25 alpha/CAB39 |
| Short name: | MO25 alpha/CAB39 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | MO25 a/CAB39 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 20292 |
| Gene: | CAB39 | More about : CAB39 |
| Long gene name: | calcium binding protein 39 |
| Synonyms: | CGI-66 MO25 |
| Locus: | 2q37, 1 |
| Discovery year: | 2004-07-02 |
| GenBank acession: | AF113536 |
| Entrez gene record: | 51719 |
| RefSeq identity: | NM_016289 |
| Havana BLAST/BLAT: | OTTHUMG00000133220 |
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