Tuberin Antibody, ALEXA FLUOR 488

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Catalog number: bs-3586R-A488
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: Tuberin Antibody, ALEXA FLUOR 488
Quantity: 100ul
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Long name: ALEXA FLUOR 488 Conjugated, Tuberin Polyclonal Antibody
Also known as: Anti-Tuberin PAb ALEXA FLUOR 488
Category: Conjugated Primary Antibodies
Conjugated with: 488, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: Tuberin
Specificity: This is a highly specific antibody against Tuberin
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 1600-1650/1809
Subcellular location: Cytoplasm
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tuberin
Gene ID Number: 7249
Swiss Prot: P49815
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, Implicated as a tumor suppressor, Involved in microtubule-mediated protein transport, Mutations in TSC2 lead to constitutive activation of RAP1A in tumors, Stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro, a direct activator of the protein kinase activity of mTORC1, but this seems to be due to unregulated mTOR signaling, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling, In complex with TSC1
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 499nm/519nm
Synonyms: tuberin LAM PPP1R160 TSC2
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Tuberin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Gene target: Tuberin
Short name: Tuberin Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 488
Alternative name: ALEXA FLUOR 488, Tuberin (Antibody to)
Alternative technique: antibodies
Identity: 12365
Gene: TSC4 | More about : TSC4
Long gene name: tuberous sclerosis 2
Synonyms name: protein phosphatase 1, regulatory subunit 160
Locus: 16p13, 3
Discovery year: 1989-05-25
GenBank acession: AB014460
Entrez gene record: 7249
Pubmed identfication: 1303246 7558029
RefSeq identity: NM_000548
Classification: Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT: OTTHUMG00000128745
Locus Specific Databases: TSC2 Mutation Database Tuberous sclerosis database LRG_487

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