| Long name: |
ALEXA FLUOR 555 Conjugated, Tuberin (Ser1254) Polyclonal Antibody |
| Also known as: |
Anti-Tuberin Ser1254 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Tuberin Ser1254 |
| Specificity: |
This is a highly specific antibody against Tuberin Ser1254 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser1254 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Tuberin around the phosphorylation site of Ser1254 [SL(p-S)VP] |
| Gene ID Number: |
7249 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
At least three isoforms of Tuberin exist, Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking, It may function in vesicular transport, It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, Mutations in tuberin lead to constitutive activation of RAP1A in tumors, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors, is implicated as a tumor suppressor, or TSC2 (Tuberous sclerosis complex), suggesting a possible mechanism for its role in regulating cellular growth, Tuberin |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
LAM, P-TSC2 Ser1254FLJ43106, P-Tuberin/TSC2 Ser1254, TSC2, TSC2 Ser1254, TSC2_HUMAN, TSC4, Tuberin, Tuberous sclerosis 2 protein, Tuberin Ser1254 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
Tuberin (Ser1254) |
| Short name: |
Tuberin (Ser1254) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, Tuberin (Ser1254) (Antibody to) |
| Alternative technique: |
antibodies |