| Long name: |
ALEXA FLUOR 488 Conjugated, Tuberin (Ser1387) Polyclonal Antibody |
| Also known as: |
Anti-Tuberin Ser1387 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Tuberin Ser1387 |
| Specificity: |
This is a highly specific antibody against Tuberin Ser1387 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser1387 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Tuberin around the phosphorylation site of Ser1387 |
| Gene ID Number: |
7249 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
At least three isoforms of Tuberin exist, Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking, It may function in vesicular transport, It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, Mutations in tuberin lead to constitutive activation of RAP1A in tumors, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors, is implicated as a tumor suppressor, or TSC2 (Tuberous sclerosis complex), suggesting a possible mechanism for its role in regulating cellular growth, Tuberin |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
LAM, OTTHUMP00000158940, OTTHUMP00000198394, OTTHUMP00000198395, P-TSC2 Ser1387, TSC2, TSC2_HUMAN, TSC4, Tuberin, Tuberin phospho Ser1387, Tuberous sclerosis 2, Tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein homolog, p-Tuberin Ser1387, FLJ43106, TSC2 Ser1387, Tuberinphospho S1387 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Tuberin (Ser1387) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Tuberin (Ser1387) |
| Short name: |
Tuberin (Ser1387) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Tuberin (Ser1387) (Antibody to) |
| Alternative technique: |
antibodies |