| Long name: |
FITC Conjugated, RSK3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RSK3 |
| Specificity: |
This is a highly specific antibody against RSK3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human RSK3/Ribosomal S6 kinase 3 |
| Gene ID number: |
6196 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB, Rsk2 and Rsk3, Rsk3 is a distinct isoform of p90Rsk that translocates to the cell nucleus, Ser363 and Thr573, Several sites, These are broadly expressed serine/threonine protein kinases that are activated in response to mitogenic stimuli, Thr359, are important for its activation, including extracellular signal-regulated protein kinases Erk1 and Erk2, phosphorylates potential nuclear targets and may have a unique upstream activator, such as Ser380, which includes Rsk1, RSK3(Ribosomal S6 kinase 3)is a member of a family of 90-kDa ribosomal protein S6 kinases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
RSK RSK3 HU-2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RSK3 Conjugated |
| Short name: |
FITC Conjugated, RSK3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, RSK3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10431 |
| Gene: |
RPS6KA2 |
More about : RPS6KA2 |
| Long gene name: |
ribosomal protein S6 kinase A2 |
| Synonyms gene name: |
90kD, polypeptide 2 , ribosomal protein S6 kinase |
| Locus: |
6q27 |
| Discovery year: |
1994-07-11 |
| GenBank acession: |
L07598 |
| Entrez gene record: |
6196 |
| Pubmed identfication: |
8141249 |
| RefSeq identity: |
NM_021135 |
| Classification: |
Mitogen-activated protein kinase-activated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000016007 |