| Long name: |
RSK3 Primary Polyclonal Antibody |
| Also known as: |
RSK3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RSK3 |
| Specificity: |
This is a highly specific antibody against RSK3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RSK3/Ribosomal S6 kinase 3 |
| Gene ID number: |
6196 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB, Rsk2 and Rsk3, Rsk3 is a distinct isoform of p90Rsk that translocates to the cell nucleus, Ser363 and Thr573, Several sites, These are broadly expressed serine/threonine protein kinases that are activated in response to mitogenic stimuli, Thr359, are important for its activation, including extracellular signal-regulated protein kinases Erk1 and Erk2, phosphorylates potential nuclear targets and may have a unique upstream activator, such as Ser380, which includes Rsk1, RSK3(Ribosomal S6 kinase 3)is a member of a family of 90-kDa ribosomal protein S6 kinases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
HU 2, KS6A2_HUMAN, MAP kinase activated protein kinase 1c, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, MAPKAPK1C, RPS6KA2, RSK 3, RSK-3, Ribosomal S6 kinase 3, Ribosomal protein S6 kinase alpha-2, S6K alpha, S6K alpha 2, S6K-alpha-2, p90-RSK 2, p90RSK 2, p90RSK2, pp90RSK 3, pp90RSK3, 90 kDa ribosomal protein S6 kinase 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RSK3 |
| Short name: |
RSK3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RSK3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10431 |
| Gene: |
RPS6KA2 |
More about : RPS6KA2 |
| Long gene name: |
ribosomal protein S6 kinase A2 |
| Synonyms gene name: |
90kD, polypeptide 2 , ribosomal protein S6 kinase |
| Synonyms: |
RSK RSK3 HU-2 |
| Locus: |
6q27 |
| Discovery year: |
1994-07-11 |
| GenBank acession: |
L07598 |
| Entrez gene record: |
6196 |
| Pubmed identfication: |
8141249 |
| RefSeq identity: |
NM_021135 |
| Classification: |
Mitogen-activated protein kinase-activated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000016007 |